1) embryo quality on day 3 after oocyte retrieval (good quality vs. poor quality) and clinical pregnancy rate.
2) clinical pregnancy rate.
In an intention-to-treat analyses, a higher rate of women with at least one good quality embryo (with at least 6 cells and a fragmentation rate <20%) were found for the study (29/50, 58.0%) compared to the control group (18/50, 36.0%; p = 0.045 in chi-square test; relative risk 1.611, 95% CI 1.009–2.597).
That data of the studies show that the nutritional support by Profertil® female supplementation, given for a minimum of 28 days prior to ovarian hyperstimulation, is beneficial in terms of fertilization rate and embryo quality.
After minimum intake duration, prior to ovarian stimulation, and with no side effects, Profertil® female demonstrated the beneficial influence of the nutrients: