Subfertility caused by unhealthy lifestyle

Where no medical reason is diagnosed for infertility, modern science assumes that infertility is primarily caused by diet and lifestyle.

Being overweight or obese

Being 22lbs (10kg) overweight increases the risk of infertility by 10%. Particularly the increase in abdominal fat leads to a reduction of free, biologically active rate of testosterone.

Smoking

Smoking affects sperm density, sperm motility (movement) and sperm morphology (appearance). A direct effect on testicular function and spermatogenesis is suspected. Metabolites of cigarette smoke components may induce an inflammatory reaction in the male genital tract, which in turn can result in oxidative damage to the sperm due to reactive oxygen radicals.

Alcohol

Severe chronic alcohol abuse can be directly toxic to the testes. It manifests itself in spermatogenesis arrest including Sertoli cell-only syndrome as well as abnormal sperm motility and morphology

Nutrition

There is a specific higher requirement for certain nutrients for spermatogenesis. An inadequate supply can lead to the development of nutritional deficiencies and subsequently to reduced sperm quality. Vitamins and micronutrients, in particular, which the body must get from food, serve as a cofactor for the enzyme reactions and have an antioxidant effect.

Subfertility and infertility caused by dietetic and lifestyle factors affect mainly the testicles (testicular disorders) and the hypothalamic-pituitary-gonadial axis. In 25% to 50% of all subfertile men a specific, pathological reason for the limited sperm analysis cannot be found. The majority of these cases are not related to a hereditary defect, a constitutional disorder or an acquired pathology (e.g. infection). Rather, the pathological sperm analysis is the result of a nutritional supply deficieny, a dysregulation of the energetic and nutritive supply, as well as a mainly nutritive, but also lifestyle-related, impairment of the cell protection, such as oxidative cell stress.